VitrificationVitrification is a process of converting a material into a glass-like amorphous solid which is free of any crystalline structure.
Despite successful vitrification of human ova and blood vessels this method was not successful for cryopreservation of mammalian internal organs because of its toxicity (Song et al., 2000; Karlsson, 2002).
Vitrification of the human internal organs (kidney, heart) is currently very much a matter of speculation.
Vitrification requires the impregnation of biological tissues with high concentrations of cryoprotective chemicals that promote the vitreous state, but these are somewhat toxic. While vitrification prevents the hazardous effect of ice formation, new potential mechanisms of injury associated with the amorphous state have been identified. Devitrification (ice formation during warming) is another major obstacle to successful organ vitrification.